What are the antibodies on the thyroid glands peroxidase?
When the body attacks certain parts of its own thyroid gland, it can be ascertained in the presence of abnormal molecules called antibodies on the thyroid gland peroxidase (TPO). Other terms for these substances are antihyroid microsomal antibodies or anti -orxidase antibodies. Increased levels are most closely associated with camouflage thyroiditis, but can also be seen with Graves' disease. A certain percentage of asymptomatic people without problems of the thyroid tested positive for this antibody, and these people are exposed to the increased risk of developing thyroid abnormalities in the future.
In general, the presence of antibodies of thyroid peroxidase in the blood is abnormal. Antibodies are proteins created by the immune system that help fight bacteria or other threats to the health of the body. Although the body usually produces only antibodies against foreign substances, in a certain class of diseases called autoimmune disorders that the body makes antibodies against the elements of its. When producing antibodies tIt produces a protein on the body that attacks the molecule important for thyroid function, the enzyme of the thyroid peroxidase. This substance is essential for creating thyroglobulin, a protein that carries the thyroid hormone through the blood into the distant parts of the body.
The positive result for the presence of thyroid antibodies is most common in autoimmune thyroiditis, which is also known as Hashimoto's thyroiditis. Patients with this disease create antibodies that attack the thyroid gland. Finally, they experience a reduction in thyroid hormone production, a condition known as hypothyroidism. Many doctors believe that finding positive TPO antibodies in a patient who has hypothyroidism as a diagnosis of Hashimot's thyroiditis. The basis of the treatment is to provide the patient with a flexible thyroid hormone in the form of a pill.
having antibodies of thyroid peroxidase is also associated witha number of other conditions. Patients with Graves disease, autoimmune thyroid disorder that causes the thyroid overproduction of the thyroid hormone overproduction may have thyroid antibodies present in their blood. Some studies indicate that women producing this antibody are exposed to an increased risk of developing reproductive problems such as early birth, abortion and infertility.
Some normal, asymptomatic people may have detectable levels of antibodies on the thyroid gland peroxidase. Up to 5 to 10 percent of the general population would have positive results in this laboratory test if checked. Although many times these people have no symptoms, problems with their thyroid function could be endangered in the future. Some doctors check this level of antibody before starting certain drugs that could lead to hypothyroidism, including Amiodarone and Lithium, as they could decide that these drugs do not use threatening in patientsProblems of thyroid hormones.