What is the difference between Pemphigus and Pemphigoid?

Pemphigus and Pemphigoid are two similar but different diseases. Both are diseases of the immune system, attack different cells and both cause blisters, even if they differ in the types of blisters they cause, their location. Both diseases are incurable, but the treatment of blisters helps to reduce symptoms. Pemphigus attacks cells called desmogleins, which are special protein cells in the skin that combine skin cells together. The blisters occur when desmogleins are separated. On the other hand, Pemfigoid focuses collagen proteins. Although the symptoms of these two diseases are similar, there are several differences. Pemphigus blisters occur in the outer layer of the skin, called the epidermis, and in layers of membranes that line the organs called mucosal membranes. Pemphigoid blisters occur where the epidermis and another layer called the dermis are connected. Pemphigus blister is fragile, breaks easily and leaves raw skin. Pemphigoid blister is tight and does not deserve easily but backPain and itching is inappropriate. Pemphigus blisters break more easily than Pemphigoid blisters mainly because of their position in the epidermis. Pemphigoid blisters are more padded.

Pemphigoid and Pemphigus have individual types of diseases. The types of these diseases are classified according to the parts of the body, where the blisters appear primarily. Both diseases have in common and rare forms.

Pemphigus vulgarus (PV) is a common type of pemfig and causes blisters in the mouth. It has been found to occur in people aged 40 to 60.Pemphigus foliaceus (PF) is a type that causes blisters that start on the skin of the head and progress to the face, back and chest. There are generally no blisters in the mouth. Paraneoplastic Pemfigus (PNP) is rare but more serious because it seems like a complication of lymphoma and causes irreversible lung damage.

also referred to as autoimmune skin disease connective tissue, pemphigoid has three different onespy. Gestational pemfigoid occurs at the end of pregnancy or immediately after delivery. Balllou Pemphigoid (BP) results in blisters on the upper arms, inner thighs and chest. Pemfigoid mucosa (MMP), also known as Cicatricial Pemfigoid, is commonly found in people aged 40 to 70 years. The nearby only occur in the organs mucosa and can cause scars that have the potential to lead to disability.

Pemphigus and pemphigoid treatment is similar. There is no medicine for any disease. However, it is possible to control the outbreaks of blisters. Topical and oral steroids are the first line of defense. Corticosteroid ointments help relieve itching and inflammation, while oral steroids help reduce the reactions of the immune system.

If steroids are not effective, immunosuppressive drugs may be necessary. These drugs treat more serious cases of Pemfig and Pemfigoid, which initially do not respond to corticosteroids. Immunosuppressive drugs are often prescribed temporarily and treatment continues with steroids. For the outbreaks that are up toBound by infection or endangered by the development of infection, antibiotics are prescribed.