Is it safe to use pseudoephedrine during pregnancy?
It may not be safe to use pseudoephedrine during pregnancy, but women should consult with their doctors before the final decision. The use of this drug during the first trimester of pregnancy was not convincingly associated with any harmful congenital defects. The US Food & Drug Administration (FDA) Does Not Believe that Eunhg Conclusive Testing on Human Patients Has Been Conduited to Rate the Drug As Safe CATEGORY C. CATEGORY AND IS GIVEN TO DRUGS THAT HAVE BEEN TESTED EXTENSIVELY AND HAVE FAILED TO SHOW ANY SIGNS OF DAMAGE TO THE MOTHER or FETUS DURING EITHER THE FIRST TRIMESTER, OR ANY The following period of pregnancy. Medicines receive category B assessment, which have been tested on pregnant animals and have not shown any evidence of damage to the mother or child, but were not tested in any human pregnant patients. Category C is given to those drugs that have damagedTka or fetus during pregnancy in animal studies and which were not tested in any human pregnant patients. Categories D and X are reserved for drugs known to cause fetal abnormalities and can endanger the health of the mother in human and animals testing.
Category C evaluation Assigned FDA regarding the use of pseudoephedrine during pregnancy suggests that the benefits of a drug for the mother may in some cases outweigh possible side effects. Testing animals, albeit by the predecessor of human testing, does not always bring the same results. A pregnant rat can give birth to a deformed child when he serves pseudoephedrine, while a pregnant human mother who has the same birth of drugs as a perfectly created and healthy child. However, the risks associated with this drug during animal testing may be unlikely in human patients.
Possible side of Effumesi use of pseudoephedrine during pregnancy PAthra gastroschisis and thin intestines atresia. Gastroschisis is a condition caused by the failure of the child's abdominal wall during development has completely closed. This opening is usually next to the umbilical cord and some of the child's intestines can push through the hole. This condition is detectable by ultrasound and can be repaired by surgery relatively soon after birth.
The small intestine atressia occurs when some of the small intestines are either closed or disconnected. This condition can also be detected by ultrasound or diagnosed immediately after birth. Newborns with this condition often have a large, spread stomach, which indicates the inability of waste to pass through the intestines. This type of defect is generally corrected by surgery soon after birth.
These diseases are associated only with the use of pseudoephedrine in pregnancy and are not convincingly associated with the drug. Other medicines and genetic factors cannot be overlooked in cases where these defects have been detected. The fetus completes most of its muscleEat, nervous and skeletal development during the first trimester of pregnancy. Some doctors may feel that the use of this medicine in later stages of pregnancy, such as the second or third trimesters, pose less risk for the child and provide a significant advantage to the mother and can recommend its use for their patients.