What are the signs of overdose of benzodiazepine?

Symptoms of benzodiazepine overdose may include an unusual sedation along with paradoxical symptoms such as anxiety and agitation. These drugs must be used in high doses to cause the symptoms and overdose of benzodiazepines cleanliness are rarely fatal, even if they still require medical treatment. More concerns may be cases where patients use these drugs along with alcohol, opioids and other depressive central nervous system agents. A combination of drugs may be enough to cause serious complications, including coma and death. Patients may accidentally develop benzodiazepine overdose if they take too many medicines or intentionally because they abuse drugs or try suicide. Symptoms may take up to four hours for drugs to walk through the body and begin to bind to a particular neurotransmitter receptors. The patient may also have a carefree speech and unstable operation, along with confusion and poor balance. These drugs can also slow breathing and heart rateI, which is a reason for concern because the patient does not have enough oxygen. Some overdose can cause agitation and anxiety and the patient may become militant or aggressive. There may also be nausea and vomiting and there is a risk of aspiration to vomit because the patient is not fully alert.

Symptoms of benzodiazepine overdose are indicators to take the patient to the patient to the hospital for treatment. It is useful to bring any regulations used by the patient because they can be useful for medical providers in the hospital. If the patient drank or used other medicines, including recreational drugs and someone else's regulation, it is important to provide this information. Concerns about serious drug interaction are a problem if the patient combined benzodiazepines and other medicines, and this may change the approach to treatment.

Treatment of first line for benzodiazepine overdose is usualLE with supporting care, including ventilation, if necessary for the patient to help breathe. For the stabilization of the patient, fluid can be provided and hospitalization can be recommended to monitor. Especially if an overdose is associated with depression and suicidal thoughts, mental health evaluation can be recommended. Flumazenil, benzodiazepine antagonist, can be used in a patient who does not have a history of dependence on benzodiazepine; However, it can be dangerous and can cause seizures, so it is usually not recommended.

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