What is Alendronate?

Alendronate is a prescription drug used to treat osteoporosis and other disorders that cause bones to become weak and fragile. It works by inhibiting osteoclasts, cells that trigger the decomposition of bone tissue. As a result, bone tissue is able to maintain important minerals and the risk of random fractures will decrease significantly. The drug is commonly sold under the Fosamax® brand, but general varieties are widely available. Alendronate comes in the form of a tablet and a liquid solution that can be mixed with water. Osteoclasts normally regulate the density and bone size by removing excess minerals, a process called bone resorption. Alendronate prevents resorption from binding to cellular areas where osteoclasts are activated. Once the bone resorption is stopped, minerals such as calcium are complemented, and the tissue can be more stronger. It usually takes several months for bioposphonates to create noticeable bone density changes. Medicines can also be prescribed to people who suffer from a condition known as Paget's disease.People with Paget's disease experience painful physical deformities due to somewhat spontaneous bone death and unusual growth. When Alendronate is used according to the doctor's instructions, most patients can be effectively controlled by osteoporosis and Paget's disease.

There is little risk of adverse side effects in the use of Alendronate, but some patients experience mild stomach seizures, nausea and constipation. Less commonly can cause chest pain, jaw pain and vomiting. Allergic reactions are rare but potentially serious. A person who is experiencing a widespread skin rash, dizziness of magic, or difficulty breathing after taking the drug should immediately visit the emergency room.

doctors are cautious when prescribing Alendronate to minimize the risk of negative side effects and drug interactions. Doctors generally start patients at low doses of drugs and within a few weeks of POSThey bluntly increase the amount of dosage. Most patients are instructed to take one daily dose of 10 milligrams, but a weekly 70 milligrams are also available. The exact amount of dosage may vary depending on the patient's specific condition, age and drug tolerance. Because both osteoporosis and Paget's disease are chronic states, people usually have to stay for the rest of their lives on the drug regime to avoid recurring bone problems.