What are serotonin and norepinephrine?
serotonin and norepinephrine are two neurotransmitters that are identified as a strong effect on mood and many forms of mental or other diseases, jointly or separately. If these chemicals exist in suitable quantities and receptors in the brain are not used too fast, it often corresponds to a more even mood. If used (reuing) too quickly, it may be difficult to control mood and may occur conditions such as depression or anxiety. It seems that to a greater or lesser extent they also have an impact on conditions such as ADHD hyperactivity disorder (ADHD), obsessive-compulsive disorder, or diseases that cause chronic pain such as fibromyalgia. Depending on the condition, medicines may be required to prevent rapid reuptake of one or both neurotransmitters.
Although serotonin and norepinephrine have similar roles, they are not the same. Most serotonin is based in the gastrointestinal (GI) system and helps in the function of the GI tract. DrugsThey take the levels of this neurotransmitter (selective inhibitors of reuing serotonin or SSRI) can sometimes cause stomach problems. The main location of most serotonin also offers an explanation of why the consumption and mood of food is sometimes related. Only about 20% of serotonin in the body circulates the central nervous system.
On the other hand, norepinephrine produced in the sympathetic nervous system and can be released in high quantities with the adrenal glands during combat or flight response. In addition to affecting mood stability, norepinephrine also seems to help increase cognitive focus. Antidepressant drugs used in the treatment of ADHD are often ineffective unless they initiate reuction of norepinephrine.
drug research has led to numerous drugs that specifically focus on serotonin levels. With the advent of tricycling, some medicines began to act as inhibitors of reuptakeRotonin and norepinephrine. This meant that they prevented receptors for these chemicals too quickly starting the reuptake process, allowing the brain more access to available serotonin and norepinephrine. Tricyclics had a heavy load of side effects and was replaced by drugs that only affected serotonin - SSRIS.
It was obvious that many people with depression or anxiety did not help SSRI fully, and researchers from drugs developed a new set of drugs that again dealt with serotonin and norepinephrine. These are called inhibitors of reuing serotonin and norepinephrine or SNRI. Venlafaxine (Effexor®), Desvenlafaxin (Pristiq®) and Duloxetin (Cymbbalta®) are currently available among common SNRIS. Several tricycles are a re-zero like SNRIS, and it is not clear that the side effects of the side effects and SNRI are really so different.
ALSO research suggests that certain conditions respond better to SNRIS. Phobia, adhd, generalized anxiety disorder and major depressionThe disorder could be best treated with the inhibitor of the reuptake of serotonin and norepinephrine. This is not always the case and treatment differs from the individual. There are disadvantages of drugs that simultaneously affect both neurotransmitters, including the tendency to create interruption syndrome, which is a similar download. In addition, inappropriate use of SNRI in people with undiagnosed bipolar disorder can easily create mania or hypomania.