What is the use of buprenorphin and naloxone?
The combination of buprenorphin and naloxone is an alternative to the treatment of opioid dependence. This medicine helps to relieve the signs of the collection that occurs when the individual stops taking opioid drugs. It is a sublingual orange tablet or a film placed under the tongue, usually taking place once a day. In most cases, patients begin to treat buprenorphin itself, which was taken in the presence of a healthcare provider before switching to combined tablet buprenorphin and naloxone. In the United States, this pairing is launched under the name Suboxone® and in October 2002 it was approved by food and drug administration. Opioid drugs have therapeutic indications, including analgesic effects, but some individuals use them, and eventually become addicted to them. Such opiates include morphine, heroin and painkillers such as codeine and oxycontin. A dependent individual is unable to stop using opiates and will suffer from a wide range of withdrawal symptoms if it is stopped or reduced.Symptoms of abstinence do not endanger life; often start within 12 hours of the last dose; And it extends from anxiety to muscle pain, vomiting and sweating.
The treatment of Suboxone® is generally effective for symptoms of abstinence opiates. It can shorten the detoxification process and can also be administered to patients as part of the long -term maintenance regime. It is designed specifically to reduce abuse of opiates of individuals.
buprenorphine is an opioid partial agonist and naloxon is an opioid antagonist. The first is in fact opioid, but at low doses it causes enough opiate effect, which allows the patient to stop taking anything stronger opioid on which he is dependent without suffering many withdrawal symptoms. As a result, buprenorphine can cause physical dependence itself so patients should not suddenly stop taking Suboxone®.
naloxone counteracts the depression of central nervous SYstool. It has been added to Suboxone® to discourage patients with detoxification from grinding their buprenorphin tablets and combining and abuse with other opiates. This medicine is sometimes distributed as part of the emergency overdose of heroin users as it may face the effects of opioid overdose.
Since some patients do not tolerate naloxone well, treatment usually begins with low doses of buprenorphin itself administered in a medical facility. The health physician will then increase the buprenorphin dose within a few days before switching to buprenorphine and naloxone. Buprenorphine and Naloxone tablet or film are usually taken once a day and is placed under the tongue until it is dissolved, often in two to 10 minutes. A film or tablet may have a citrus or fruit taste and should not be chewed or swallowed whole.
The most serious potential side effect of buprenorphin and naloxone is to break problems that may be life -threatening. Patients who feel dizziness do notBO confused or slowing breathing should immediately seek medical care. The use of buprenorphin and naloxone with a sedative, trance or antidepressant can cause overdose. Drinking alcohol when using buprenorphin and naloxone can lead to loss of consciousness and death.
Other potential side effects Suboxone® include drowsiness and dizziness. Patients may develop problems with jathers or notice a reduction in blood pressure. Headaches, vomiting and insomnia were also reported. The use of buprenorphin and naloxone can lead to dependence and abuse because buprenorphine is opioid.
As with any drugs, patients should discuss previous or ongoing health problems with their doctors before starting Suboxone®. The patient should detect all medicines, vitamins and supplements he takes. Individuals with a backbone that affects breathing or WHO are pregnant or can conceive should proceed with caution when considering buprenorphin and naloxone.