What is an organic acid test in the urine?

Organic acid test in urine is performed for screening of people for certain inherited metabolic disorders, which are classified as organic akysemia or organic aciduria. These test screens for the presence of abnormally high levels of metabolic products whose presence indicates the likelihood of a congenital metabolism error. Urine is collected and controlled for the presence of abnormal levels of organic acids, usually using gas chromatography with mass spectrometry. In most cases, organic acid tests identify up to 63 different substances as normal or increased.

Organic akysemia usually occurs in infant or very early childhood, causing a wide range of symptoms. Indicators may include lethargy, seizures, vomiting and inability to prosper. Symptoms of metabolic problems may be gentle, but may also be the basic cause of other significant health problems, including liver failure, coma and osteoporosis. HarmOther organs are common, as is the destruction of parts of the central nervous system. Although symptoms can be treated, it is usually necessary to use urine test for organic acids to detect the reason for problems and determine the most effective treatment.

Since there are more than five dozen of organic acidemies, it is important that it tests organic acid urine to test a wide range of acids that may indicate the presence of one or more. Three of the main types of acidemia are diseases of the urine of maple syrup, methylmalone akysie and propion acidemia, although other types may be present separately or in combination with them. One of the difficulties of using urine test on organic acids is that the problem may be intermittent, resulting in inaccurate test results; Some urine samples will not have any excess organic acids present, but instead they will display a normal level. IfAcidemic is still suspicious, the best course is that the doctor collects urine from different days and times and checks them all.

When organic akysherimia was identified, it is necessary to start treatment as quickly as possible. In some cases, the prognosis is death and in most cases treatment is to use effective supporting care, because in many cases there is nothing for this situation to do. Care includes things such as a limited diet, usually containing several proteins and a very high content of carbohydrates, replacing amino acids and vitamin therapy. Patients may also require intravenous fluids and, in some cases, must be fed with stomach tube instead.