What are insulin antibodies?

Insulin is a hormone secreted by pancreatic beta cells in response to an increase in blood or sugar glucose. When a large amount of glucose enters the bloodstream, insulin promotes the absorption of glucose through the liver, which converts glucose into its storage form, glycogen. The presence of insulin antibodies in the bloodstream suggests that the body mounts an immune response to an external, injection insulin or its own insulin. Insulin antibodies bind to insulin, preventing insulin from interacting with normal places of effect. As a result, blood and urine glucose levels increase, leading to classic symptoms of diabetes mellitus type 1, such as increased thirst, frequent urination and increased appetite.

type 1 diabetes occurs when the body attacks its own beta cells of insulin in the pancreas. Although type 1 diabetes is called juvenile diabetes due to its frequent occurrence in childhood, scientific testing on insulin antibodies wave resultUtoimmune diabetes of adults (Lada). Up to 20 percent of adult diabetic patients, probably with diabetes 2. Doctors may distinguish between these two entities by testing insulin antibodies, with Lada patients usually test for these antibodies. Type 2 diabetics have high levels of circulating insulin and rarely test positive for insulin antibodies.

insulin resistance is the condition characterized by the need for more than 200 units per day insulin to control blood sugar levels. This insulin resistance is most often related to the production of circulating immunoglobulin G (IgG) antibodies against insulin for almost every diabetic that injures insulin. Antibodies can almost increase up to 1000 times higher than the normal amount of 0.1 percent of insulin users. Change from one form of insulin to another rarely helps because protrumIlls strongly bind to pork, beef and human insulin. Insulin resistance persists for less than a year, while antibodies gradually fall to normal.

There are two possible insulin antibodies treatments in the United States. Steroids such as Prednison alleviate insulin resistance, perhaps by suppressing an immune response. In addition, insulin Lispro is resistant to antibodies, thanks to the changed shape, these two treatment are useful during the period of insensitivity of insulin. Reactivity to insulin can suddenly return, which makes these patients the possibility of hypoglycaemia with a serious problem.